Overview

This course introduces the scientist to Bioinformatics, which uses computer databases to store, retrieve and assist in understanding biological information. Genome-scale sequencing projects have led to an explosion of genetic sequences available for automated analysis. These gene sequences are the codes, which direct the production of proteins that in turn regulate all life processes. The student will be shown how these sequences can lead to a much fuller understanding of many biological processes allowing pharmaceutical and biotechnology companies to determine for example new drug targets or to predict if particular drugs are applicable to all patients. Students will be introduced to the basic concepts behind Bioinformatics and Computational Biology tools. Hands-on sessions will familiarize students with the details and use of the most commonly used online tools and resources. The course will cover the use of NCBI's Entrez, BLAST, PSI-BLAST, ClustalW, Pfam, PRINTS, BLOCKS, Prosite and the PDB. An introduction to database design and the principles of programming languages will be provided.

Course Details

Textbook (for in-class version only)

Prerequisites

Required: Basic molecular biology (e.g. a basic understanding of DNA, RNA, proteins, transcription, and translation). Recommended: Computer Skills for Biologists or equivalent knowledge/experience;

Course Materials

Additional Bioinformatics Information Resources