Introduction to Bioinformatics

OVERVIEW

Quarter: Summer 2002

This course introduces the scientist to Bioinformatics, which uses computer databases to store, retrieve and assist in understanding biological information. The human genome-sequencing project will lead to a preliminary description or sequencing of all genes in a variety of organisms, including humans. Gene sequences are the codes, which direct the production of proteins that in turn regulate all life processes. The student will be shown how these sequences can lead to a much fuller understanding pharmaceutical companies to determine if particular drugs are applicable to all patients. Examples will be presented to the student of how Bioinformatics as a drug discovery tool will, dramatically increase the number of potential biological target for a drug's action (which is almost always a protein) to be identified and studied for drug development.

Instructors: Petar Stojadinovic, Ph.D.
Helge Weissig, Ph.D.
Project Leader, Bioinformatics
ActivX Biosciences, Inc.

COURSE MATERIAL

previous courses: Spring 2000, Winter/Spring2001, Summer2001, Fall2001, Winter2002, Spring 2002

1st Session
Lecture: HTML, PDF
References: Bioinformatics - Introduction; M. Gerstein, Yale
Bioinformatics - Sequence; M. Gerstein, Yale
Additional Material: Genetic Analysis Tools on the Internet
Dynamic Programming Ttutorials:
2nd Session
Lecture: morning session: Protein Analysis
afternoon session (powerpoint slides):HTML, PDF

the "other stuff"
References: SQL for Dummies; A.G. Taylor, IDG Books Worldwide; ISBN: 0764501050 - very nice introduction to SQL
Using SQL; R. Colburn, QUE; ISBN: 0789719746 - intermediate to advanced level and very thorough! Provides many examples for different RDBMs.
Web Developers Virtual Library: Databases
Additional Bioinformatics Information Resources
Reading Materials: A list of useful Bioinformatics books
Structural Bioinformatics Text Book (coming soon!)
Further reading materials
Molecular Biology Glossaries and Dictionaries:
Other Links  
Related Courses by the Instructor
Computer Skills for Biologists
Introduction to Structural Bioinformatics

FINAL EXAM